Research Studies

We are currently conducting several studies on different aspects of depression and suicide risk. Read more about our currently active studies below:

1. Brief Skills for Safer Living (B-SfSL) Study

Project Lead: Dr. Sakina Rizvi
Graduate Student: Onjoli Krywiak
Research Coordinator: Anna Kiriakidis

Seeking: Adults across Canada who are currently experiencing suicidal thoughts and would like to contribute to a mental health research study.

The purpose of this randomized controlled trial is to evaluate the Brief Skills for Safer Living (B-SfSL) intervention—a one-time, online therapeutic session led by a psychotherapist that focuses on supportive, skills-based strategies for managing suicidal thoughts and increasing personal safety.

This fully virtual study includes five visits over approximately three months. Participants complete a therapeutic session, clinical interviews and questionnaires, computer-based tasks, and a feedback interview. As part of the randomized design, participants are assigned to receive the therapeutic session either shortly after enrollment or following a 3-month interval.

Compensation is provided to participants who complete study procedures.

You may be eligible if you:
• Are 18 years of age or older
• Are experiencing suicidal thoughts within the past week
• Are not currently receiving psychotherapy services

To see if you are preliminarily eligible, please complete our pre-screening survey: https://redcap.smh.ca/redcap/surveys/?s=KAAHM7W8NHCLN8XT

For more information, contact onjoli.krywiak@unityhealth.to or anna.kiriakidis@unityhealth.to.

2. Dopamine and the brain study

Project lead: Dr. Sakina Rizvi, PhD student: Leen Ghanayem

Seeking: Healthy controls, individuals with treatment resistant depression, and individuals with non-treatment resistant depression.

The purpose of the study is to investigate the dopamine network in the brain across individuals with treatment resistant depression, non-resistant depression and controls. Currently, we are seeking participants from all 3 groups to participate. You may be eligible if you are between 25-55 years old and:

Treatment resistant depression group: Are currently depressed, not currently taking antidepressant medication, and have failed to respond to at least 2 antidepressant medications in your current depressive episode.

Non-resistant depression group: Are currently depressed, not currently taking antidepressant medication, and have previously tried antidepressant medications that have worked.

Healthy control group: have no psychiatric history, and are otherwise healthy.

Participation involves undergoing 2 brain scans (Magnetic Resonance Imaging and Positron Emissions Tomography), completion of cognitive tasks and clinical scales. Total time commitment is ~7 hours. Compensation will be provided for participants who complete the study procedures.

For more information, email connect@asrlife.ca.